2.7 Statistical methodology.
Data were presented as mean values with standard error of mean, or
median with interquartile ranges for non-Gaussian data. Unless otherwise
stated, one way ANOVA was utilized to assess the differences in
distribution among groups with quantitative dependent variables and the
Chi-square test for categorical variables. Differences in platelet
anti-aggregatory responses to SNP between control subjects and patients
were evaluated using ANOVA followed by Bonferroni test, and the measured
differences within the patients’ blood/plasma samples during acute and
chronic or acute and post-NAC phases were assessed by Student’s paired
t-test. Data comparisons for SD-1 concentrations (acute, with/without
NTG/NAC therapy and chronic) and control subjects also utilized ANOVA
with post-hoc specific comparisons (Bonferroni test) or Student’s paired
t-test as appropriate. All tests were 2-tailed and data were expressed
as mean ± SEM, unless otherwise stated; p values ≤ 0.05 were considered
statistically significant. Data analyses were performed using SPSS 23
version software.