Figure Legend
Fig 1. Raised proinflammatory responses in diabetics with latent TB. EC, Endemic control; LTBi, latent TB; DM, diabetes mellitus; DM-LTBi, latently infected diabetics; TB, tuberculosis. Total cellular RNA was extracted from PBMCs subjected to RT-PCR using sequence-specific primers to IFN-γ, TNF-α, IL-6, and SOCS-3. All mRNA expression levels were normalized to the housekeeping gene HuPO, and data calculated as median Target gene ⁄ HuPO by the relative quantification 2ΔΔC t method. Data is depicted as bar graphs for each group with median values indicated by a horizontal line. *Denotes a significant difference (≤0.05) between the groups using Mann–Whitney U-test. Figure shows A. IFN-γ, B. TNF-α, C. IL-6 and D. SOCS-3.