Mycobacterial antigen-induced IL-13 and IL-5 levels are raised in DM-LTB cases
To investigate the effect of mycobacterial antigens on type 2 cytokines we measured PPD-induced secretion of IL-13, IL-5 and IL-4 in DM and EC cases with and without LTBi. PPD- stimulated IL-5 (p=0.025) levels were found to be differ between study groups (Table 3). PPD-stimulated IL-5 levels were also raised in DM-LTBi as compared with EC (p=0.0288). IL-13 levels were significantly increased in DM-LTB as compared with DM (p=0.0093). IL-4 secretion was not detected in the supernatants studied.