What this study adds:
- A novel compound, phormidin has been found to be Fatty Acid Synthase
inhibitor.
- Phormidin showed better cytotoxicity with A549 cell line than
cerulenin and C75.
Clinical significance :
- Phormidin is stabler than Cerulenin, more active than C75 and
predicted less toxic.
- Phormidin can be further re-engineered as a good lead molecule for
suitable uses.