Age
It’s largely known that advance age negatively affects fertility. As age
increases, fecundity decreases. The fecundity of women decreases
gradually after 32 years but it significantly decreases after 37
years.(15) The reason of age related decreasing fertility may because of
altered ovarian reserve and metabolism. In a prospective study about
women age and ovarian reserve, altered follicular metabolism was found
in women with either reduced ovarian reserve or advanced maternal age.
(16)
Presence of endometriosis has also detrimental effect to ovarian reserve
by itself. Our ERROR (Endometrioma Related Reduction in Ovarian Reserve)
study showed that women with endometrioma experience a progressive
decline in serum AMH level, which is faster than in healthy women. Thus,
both presence of endometriosis and advanced age may have negative impact
on fertility. It may be related with cycle cancellation. In our study we
found mean women age 34 (26 – 43) in CC and 30 (8 – 40) in ETC (embryo
transferred cycle) group. According to our results, women age is one of
the prognostic factors for predicting CC.