SD: Standard deviation, n: Number, BSA: body surface area
In comparison between hyperthyroid and control groups, there was no
significant difference in clinical parameters such as age, sex, and body
surface area (BSA), and two groups were matched. Hemodynamic parameters
assessment showed that, the hyperthyroid patients had a higher heart
rate compared to control group at rest, but both systolic and diastolic
blood pressures were not significantly different between the two groups.
All the subjects were in sinus rhythm without any significant ST segment
deviation.
In echocardiographic evaluation of diastolic function, we found that, no
patient had septal e’<7 or lateral e’<10cm/s and
mean values were 9.74±2.1 and 13.43±2.9, respectively. Mean E/e’ at rest
in the hyperthyroid patients was 7.2 ±1.1 that was in normal range and
also was not elevated in none of the individuals. Also, TR velocity and
LAVI met criteria for diastolic dysfunction in no patient; so, regarding
the ASE guideline definition, no one had diastolic dysfunction at rest.
(Table-2)
Diastolic indices including septal and lateral mitral annular
velocities, TR velocity, E/e’ ratio, LAVI, MPI, and PAP showed no
notable difference between the two groups; IVRT was the only parameter
that was lower in the hyperthyroid patients compared to the control
group. (P value: 0.008; Table-2)
Table -2. Comparison of clinical characteristic, hemodynamic, and
echocardiographic parameters at rest between the hyperthyroid and
control groups