Cases resource, samples collection, experimental mice
The disease occurred in a breeding farm with about 890 raccoon dogs in Guan County of Shandong Province in August, 2019; and about half of the raccoon dogs were abnormal and several decades of them showed unstable standing, dyspnea, sever swelling in some joints; and a few died for that. Some important information on this disease was recorded. Three raccoon dogs with typical symptom were carefully examined and some tissues samples were collected to be used for identifying the pathogens of this disease.
The special pathogenic free (SPF) BALb/c mice were purchased for artificial-infection-test from Experimental Animal Center of Shandong , of .