Data and analysis
Data were expressed as mean ± standard deviation (SD). Numbers for every
experiment (and group) are given in the figure legends and refer to the
number of every individual animals used in the respective group. Data
obtained from inappropriate measurements (e.g. mouse dying during blood
sampling) were excluded. Data were analyzed by one-way analysis of
variance followed by Tukey’s test using the SPSS 17.0 (IBM, USA). Note
that p-values less than 0.05 was considered to be statistically
significant (i.e.,*p <0.05, **p< 0.01, or ***p
<0.001). All data were analyzed without any transformation
except the data from ED50 measurements, which were
log-transformed.