Bullet point summary
What is already known:
dFG-5 showed potent anti-iXase and antithrombotic activity without
effects on f.XII and platelets
What this study adds:
- Oligosaccharides’ structures and contents in dHG-5 and contribute to
the pharmacological activities of dHG-5
- Pharmacological characteristics of oligosaccharides contained in dHG-5
Clinical significance:
The selective iXase inhibitor dHG-5 is a potential candidate for
treating venous thrombosis