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CD30 POSITIVE NON-LEUKEMIC VARIANT OF ADULT T-CELL LEUKEMIA/LYMPHOMA, HTLV-1 ASSOCIATED
  • Mark Podberezin,
  • Aliyah Sohani
Mark Podberezin
Lahey Hospital and Medical Center
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Aliyah Sohani
Massachusetts General Hospital
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Peer review status:ACCEPTED

09 Apr 2020Submitted to Clinical Case Reports
11 Apr 2020Submission Checks Completed
11 Apr 2020Assigned to Editor
16 Apr 2020Reviewer(s) Assigned
01 Jun 2020Review(s) Completed, Editorial Evaluation Pending
07 Jun 20201st Revision Received
12 Jun 2020Submission Checks Completed
12 Jun 2020Assigned to Editor
17 Jun 2020Review(s) Completed, Editorial Evaluation Pending
25 Jun 2020Editorial Decision: Accept

Abstract

We present a case of non-leukemic (lymphomatous) variant of HTLV-1 associated adult T-cell leukemia/lymphoma in a young woman. Tumor demonstrated strong and diffuse CD30 and PD-1 expression which is very unusual finding in this entity. Very good clinical response was obtained with brentuximab-containing treatment regimen.