Discussion
This prospective observational study aimed to explore target LI measurements at each RFA for creating sufficient ablation lesions during PV isolation. The main findings were: (1) a large LI drop (≥15 ohm) best predicted the absence of a conduction gap; (2) ablation points with an LI drop <15 ohm demonstrated short RFA time, low pre-RFA LI, and unexpected RFA suspension; (3) an LI drop was more prominent than an GI drop at ablation points without a gap; (4) GI was not correlated with LI. To our knowledge, this is the first study to report a target LI drop at each RFA for creating sufficient ablation lesions assessed by the absence of a conduction gap during PV isolation.