Results
The search terms yielded 26,782 manuscripts and were ranked in
descending order of total citations. The 100 top-ranked manuscripts had
a total of 76,680 citations and are shown in Table 1 . The list
of manuscripts is ordered from most to least cited on PubMed.gov.[6]
The number of citations ranged from 3667 to 350, with a mean and median
citation count of 767 and 533 respectively. The manuscripts were
published across 16 journals shown in Table 2 .
The journal New England Journal of Medicine (NEJM) had the
highest impact factors and generated the highest number of citations, of
22,458 with 18 manuscripts. This is followed by Circulation with the
highest number of manuscripts, of 24, generating 14,719 citations. The
latest manuscript was on management guidelines for valvular heart
diseases by the European Society of Cardiology published in 2017 issue
of European Heart Journal . The oldest manuscript was published in
Lancet in 1986 comparing percutaneous valvuloplasty against valve
replacement in patients with aortic stenosis.
The country with the most citations was the United States of America,
with 43,629 citations across 51 manuscripts. This is followed by France
and Canada, with 13,750 and 6579 citations respectively, generated by a
total of 26 manuscripts. Citations counts by country are shown inFigure 1 .
Of the top 10 authors, five have more than three authorships in the top
100 manuscripts (Table 3 ). 8 of the top 10 cited authors have
multiple manuscripts and altogether generated a total of 36,578
citations. Nashimura had the most manuscripts in the top 100 (n=6),
totalling 4,583 citations. Vahanian generated the highest citation count
of 5,178 from four manuscripts in addition to being the senior author of
two other manuscripts within the top 100.
Of the top 100 manuscripts, 33 investigated aortic valve replacement for
both aortic regurgitation and stenosis whereas 32 were specific to
aortic stenosis alone, accumulating 33,336 and 22,638 citations
respectively. 29 manuscripts focussed specifically on the outcomes of
percutaneous or transcatheter approach to aortic valve replacement,
amounting to 20,702 citations. 18 of the top 100 were management
guidelines involving aortic valve replacement, resulting in 17,585
citations. Topics by citation are shown in Table 4 .