3.4 Biomarkers associated with inflammation
The average follow-up duration was 2.7 ± 1.3 years. There were no
significant differences in the number of the WBCs, ratio of the
neutrophils, and lymphocytes before the ablation between the LRAF and
non-LRAF groups (Table 3). No significant difference was demonstrated in
the CRP level and number of platelets before the ablation between the
two groups (Table 3). After ablation there were also no significant
differences in these biomarkers between the two groups (Table 3).
The ERAF patients consisted of 203 patients (32.1%). The ΔNLR and ΔPLR
were significantly higher in the ERAF than no-ERAF group (1.464 ± 2.756
vs 0.779 ± 1.464, 6.390 ± 60.76 vs -2.751 ± 41.38, p<0.001,
p=0.027, respectively).
Between the LRAF and no-LRAF groups, the NLR after ablation and ΔNLR
were significantly higher in the LRAF and no-LRAF groups (3.747 ± 3.033
vs 3.288 ± 1.766, 1.324 ± 2.911 vs 0.896 ± 1.596, p=0.022, p=0.021,
respectively), while there were no significant differences in the NLR
before the ablation (2.422 ± 1.480 vs 2.392 ± 1.173, p=0.793, Figure1A).
The PLR after the ablation and ΔPLR were significantly higher in late
recurrence and no-late recurrence groups (147.0 ± 80.09 vs 133.4 ±
58.87, 8.993 ± 61.61 vs -2.569 ± 43.43, p=0.022, p=0.011, respectively),
but there were no significant differences in the PLR before the ablation
between the 2 groups (135.8 ± 59.65 vs 136.0 ± 53.90, p=0.981,
Figure1B).