3.4 Biomarkers associated with inflammation
The average follow-up duration was 2.7 ± 1.3 years. There were no significant differences in the number of the WBCs, ratio of the neutrophils, and lymphocytes before the ablation between the LRAF and non-LRAF groups (Table 3). No significant difference was demonstrated in the CRP level and number of platelets before the ablation between the two groups (Table 3). After ablation there were also no significant differences in these biomarkers between the two groups (Table 3).
The ERAF patients consisted of 203 patients (32.1%). The ΔNLR and ΔPLR were significantly higher in the ERAF than no-ERAF group (1.464 ± 2.756 vs 0.779 ± 1.464, 6.390 ± 60.76 vs -2.751 ± 41.38, p<0.001, p=0.027, respectively).
Between the LRAF and no-LRAF groups, the NLR after ablation and ΔNLR were significantly higher in the LRAF and no-LRAF groups (3.747 ± 3.033 vs 3.288 ± 1.766, 1.324 ± 2.911 vs 0.896 ± 1.596, p=0.022, p=0.021, respectively), while there were no significant differences in the NLR before the ablation (2.422 ± 1.480 vs 2.392 ± 1.173, p=0.793, Figure1A). The PLR after the ablation and ΔPLR were significantly higher in late recurrence and no-late recurrence groups (147.0 ± 80.09 vs 133.4 ± 58.87, 8.993 ± 61.61 vs -2.569 ± 43.43, p=0.022, p=0.011, respectively), but there were no significant differences in the PLR before the ablation between the 2 groups (135.8 ± 59.65 vs 136.0 ± 53.90, p=0.981, Figure1B).