Acknowledgments
This work was supported by the National Key R&D Program of China (Nos. 2018YFA0900600, 2018YFA0901904, 2019YFA0904803), the National Natural Science Foundation of China (Nos. 31971344, 31770037), and Shanghai Municipal Natural Science Foundation (Nos. 17ZR1448900 and 18ZR1420300). We thank Prof. Meng Wang (Tianjin Institute of Industrial Biotechnology, Chinese Academy of Sciences, Tianjin) and Ms. Bo-Na Dai of Instrumental Analysis Center of SJTU for their helpful discussion on chemical structure determination of DHLDOA. We thank Ms. Ting-Ting Liu of our laboratory for her assistance in fermentation experiments.