Exploring Current Clinical Trials for Covid-19
As of 2005, the International Committee of Medical Journal Editors
(ICMJE) has proposed that all clinical trials be reported in publicly
accessible domains before they can be accepted for publication [56].
The implementation of this provision and other efforts to improve
transparency in clinical trials has led to such a increasing number of
trials being registered in online registries, such as ClinicalTrials.gov
and the WHO’s International Clinical Trials Registry Platform (ICTRP).
Logging trials on registries has significantly promoted knowledge
sharing in many areas, including research, technique, community of
patients, and outcome measures. In addition, if the findings are not
released, it means that the trial information remains freely available
for analyzation. Under the current global COVID-19 pandemic, we
performed an electronic registry review (ClinicalTrials.gov, WHO ICTRP,
EU Clinical Trials Register, and Cochrane Central Register of Controlled
Trials) to collate all reported therapeutic and preventive procedures
under clinical investigation. We hope this will explain recent
developments in the investigation and direct possible future strategies.
Table -1 & 2 demonstrates interventional therapies and preventive
approaches for COVID-19 under clinical review.
Several registered clinical trials are currently being conducted
globally to evaluate the efficacy of the drugs against COVID-19 (Table-1
& Table 2)