Methods
W e performed a
retrospective chart review of 189 patients who were diagnosed with
recurrent NPC and treated at the Department of Otorhinolaryngology of
the AEENTH at [Blinded for review] University from January 2006 to
June 2018. Patients who had distant metastasis or missing data on
important variables were excluded. All patients underwent Salvage
endoscopic nasopharyngectomy performed by [Blinded for review].
C linical data were retrieved, including the age; sex; history
of smoking and alcohol consumption; diabetes and hypertension; body mass
index (BMI); number of radiotherapy sessions before
surgery;preoperative chemotherapy; period between recurrence and the
last session of radiotherapy; T/N-stage; pathological type; status of
tumor necrosis; overall survival rate;and serological
factors(hemoglobin (Hb) count, neutrophil to lymphocyte ratio
(NLR),and serum levels of alkaline phosphatase (ALP). In addition,
prognostic factors were assessed using the Kaplan-Meier method.
Differences in survival distributions were evaluated with the log-rank
test. The Cox regression model was used for multivariate survival
analyses. The follow-up period was from the initial diagnosis at our
institution to date of death or last contact.