Results
Eighty patients were identified with AoD. Table 1 presents population characteristics of the forty-seven (47) patients with complete data who met inclusion criteria. Thirty-five patients (74%) who were started on medication were male and White/Caucasian. A BAV was diagnosed in 40%, MFS was diagnosed in 28%, isolated AoD in 21%, TS in 4%, and LDS in 4%.
Thirty patients had genetic testing, of which 20 (67%) had a genetic anomaly identified (Table 2). Family history was significant in 40% of patients including AoD, aortic dissection, or vascular aneurysm.
Majority of patients were started on Losartan (51%), Atenolol (32%), Metoprolol ( 13%), and Lisinopril (4%). Four patients (9%) had a documented diagnosis of hypertension at the time of initiation of medication for AoD. Only one patient was not on medication at the time they underwent surgery.