1. Introduction
The unexplained clustering pneumonia cases related to the south China
seafood wholesale market were reported in Wuhan City, Hubei Province,
China in December 2019(1). China scientists isolated
novel coronavirus from patients and sequenced the genome, and found that
the genetic sequence of the virus was at least 70% similar to that of
the human severe acute respiratory syndrome coronavirus (SARS-CoV).
World Health Organization (WHO) named this novel coronavirus 2019-nCoV(2) and the 2019-nCoV causes Coronavirus Disease 2019
(COVID-19) (3). As of April 16, 2020, more than 83000
cases have been confirmed in China and 2022000 cases in the world(4).
Both 2019-nCoV and SARS-CoV are β-coronaviruses. The mortality rate of
SARS-CoV infection is 10%, among which the mortality rate of maternal
infection is 25%(5). The clinical outcome of pregnant
women is worse than that of non-pregnant women. To date, clinical data
on pregnant women infected with 2019-nCoV is still very limited.
Therefore, we conducted this systematic review and meta-analysis to
assess the clinical features and pregnancy outcomes of pregnant women
infected with COVID-19, with a view to help formulate clinical treatment
strategies for pregnant women with COVID-19.