Response
Group I (Normal) Group II (10mg/kg b.w) Group III (50mg/kg b.w) Group IV (100mg/kg b.w)
Colour Colour Colour Colour Colour
Fur N N N N
Eyes N N N N
Mucous Membrane N N N N
Urine N N N N
Behavioral observations Behavioral observations Behavioral observations Behavioral observations Behavioral observations
Mood N N N N
CNS Excitation NO NO NO NO
CNS Depression NO NO NO NO
Motor Indication Motor Indication Motor Indication Motor Indication Motor Indication
Abnormal gait NO NO NO NO
Righting reflex N N N N
Posture N N N N
Sensory Responses Sensory Responses Sensory Responses Sensory Responses Sensory Responses
Touch & pain response N N N N
Straube”s phenomenon NO NO NO NO
Reflexes Reflexes Reflexes Reflexes Reflexes
Pinnna & corneal N N N N
Autonomic effects Autonomic effects Autonomic effects Autonomic effects Autonomic effects
Defecation &Lacrimation N N N N
Urination &Salivation N N N N
Piloerection N N N N
Miosis & Mydriasis NO NO NO NO
Diarrhoea NO NO NO NO
Respiratory effect Respiratory effect Respiratory effect Respiratory effect Respiratory effect
Apnoea & dysponea NO NO NO NO
Death NO NO NO NO