BACKGROUND AND PURPOSE
Type II Diabetes mellitus (T2DM) is a worrying chronic metabolic
disorder accompanied by multiple serious complications, makes threaten
public health. In the present study, we evaluated the therapeutic
effects against T2DM of the cycloastragenol (CAG ), a key
metabolite of astragaloside IV (AST ) isolated from traditional
Chinese plant Astragalus membranaceus and revealed its molecular
mechanism.