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An Update on Novel COVID-19  Pandemic; A  Battle between Humans and Virus
  • Fallbackprofileimagethumb
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  • Suneel Prajapati,
  • Mahima Sharma,
  • Arun Kumar,
  • Pankaj Gupta,
  • Narasimha Kumar G .V.Orcid
Suneel Prajapati
Dr. DP Rastogi Central Research Institute for Homeopathy
Author Profile
Mahima Sharma
Dr. DP Rastogi Central Research Institute for Homeopathy
Arun Kumar
Dr. DP Rastogi Central Research Institute for Homeopathy
Pankaj Gupta
Dr. DP Rastogi Central Research Institute for Homeopathy
Narasimha Kumar G .V.
Orcid
Dr. Anjali Chatterjee Regional Research Institute for Homeopathy
Author Profile

Abstract

In the 21st century, human civilization, has witnessed three major epidemics caused by Coronaviruses namely severe acute respiratory syndrome coronavirus (SARS‑CoV) in 2003, Middle East respiratory syndrome coronavirus (MERS‑CoV) in 2012 and 2019‑novel coronavirus (2019‑nCoV) or coronavirus disease (COVID‑19) in 2019. Among these, COVID-19 has greater transmission and mortality rate.  2019‑nCoV belongs to a large family of positive sense single-stranded RNA viruses (+ssRNA) that can be isolated in different animal species. The most communal symptoms of COVID-19 include fever, cough, and shortness of breath during the incubation period (2-14 days) of infection. COVID-19 transmission is occurring from infected humans to close contact with one another through respiratory droplets, coughs, and sneezes of infected person. Moreover, the virus containing surfaces may also transmit the infection. Diagnosis is being carried out by collecting a nasopharyngeal swab or sputum specimen for detection of SARS-CoV-2 RNA by reverse-transcription polymerase chain reaction (RT-PCR). Rapid diagnosing methods are also under development which can diagnose COVID 19 in few minutes to hours. Currently, there is no specific cure or preventive therapeutics available. Hence, based upon limited in-vitro and anecdotal data, Chloroquine, or Hydroxychloroquine, Remdesivir, Lopinavir and Ritonavir are being employed in the management. Search for new specific anti-viral drugs from natural/synthetic origins is under full swing and many of them are currently used as chemotherapeutic drugs under clinical investigation. Yet, there is a strong need for development of vaccine, which may take several months to few years for the development.