PK and BE Analysis
PK parameters such as AUC0-t, AUC0-∞, Cmax , the elimination half-life(T1/2), and time to achieve the Cmax (Tmax ) were determined. The pharmacokinetic parameters of rasagiline were calculated with WinNonlin Version 6.4 by non-compartment model. The AUC was calculated by the linear trapezoidal linear interpolation method. The experimental results were mainly analyzed by descriptive statistics using SAS (SAS Institute, USA, version 9.4). The main pharmacokinetic indexes after logarithmic transformation were analyzed by a mixed effect model. The level of significance was set at P <0.05.