Summary
African swine fever (ASF) is emerging in Vietnam and poses a continuing
severe threat to the swine industry. A histopathological study of
clinical samples collected during the August to September 2019 outbreak
of ASF was performed to determine the characteristic lesions. We
analyzed samples from eight ASFV-infected farms. Histopathological
results revealed the characteristic lesions of the acute to the subacute
clinical form of ASF. Immunohistochemical results showed ASFV viral
antigen distribution in mononuclear cells/macrophage in various organs,
hepatocytes, and renal tubular epithelium. Molecular analysis of partial
capsid protein 72 gene revealed that ASFV strain from the eight separate
outbreaks belonged to genotype II.
Keywords: Asfarviridae, domestic pig, histopathology,
immunohistochemistry, natural outbreak