Data analysis:
Extracted data were presented in summary tables. In addition, the
following analyses were carried out:
Risk management: For each risk minimisation measure reported,
prevalence of implementing that measure was calculated as the
proportion of a study population reported to be using a measure. This
was calculated as follows:
Prevalence of risk minimisation measure implementation/ 100 patients =
total number of patients implementing the measure / total number of
patients using the teratogenic medication x 100
Perceptions of teratogenic risk : The perceived teratogenic
risk for each medication was assigned into one of three categories:
properly-estimated, over-estimated, or under-estimated (as shown
previously in Figure 1). Categorised results were presented in tabular
form.