mAb-4 (HP6002)
Figure 4 shows that mAb-4 binds to IgG2 and IgG4 proteins, but not to IgG1 and IgG3, regardless of the amount of IgG subclass coated on the beads. At the highest concentration tested (5 μg/mL), the reactivities against IgG1, IgG3, and IgG4 were respectively: 0%, 1%, and 113% that of the reactivity against IgG2 (0.5μg per 1x106 beads of IgG subclass protein); 0%, 1%, and 109% (1μg per 1x106 beads); and 1%, 4%, and 113% (2μg per 1x106 beads).