mAb-7 (HP6025)
Figure 7 shows that mAb-7 binds to IgG2 and IgG4 proteins, but not to IgG1 and IgG3. At the highest concentration tested (5 μg/mL), the reactivities against IgG1, IgG2, and IgG3 were respectively: 0%, 37%, and 1% that of the reactivity against IgG4 (0.5μg per 1x106 beads of IgG subclass protein); 1%, 59%, and 5% (1μg per 1x106 beads); and 4%, 71%, and 9% (2μg per 1x106 beads).