mAb-8 (HP6023)
Figure 8 shows that mAb-8 binds to IgG2 and IgG4 proteins, but not to
IgG1 and IgG3. At the highest concentration tested (5 μg/mL), the
reactivities against IgG1, IgG2, and IgG3 were respectively: 0%, 20%,
and 1% that of the reactivity against IgG4 (0.5μg per
1x106 beads of IgG subclass protein); 0%, 47%, and
2% (1μg per 1x106 beads); and 2%, 79%, and 4% (2μg
per 1x106 beads).