mAb-5 (HP6014)
The mAb-5 binds to IgG2 and IgG3 proteins, but not to IgG1 and IgG4, regardless of the amount of IgG subclass coated on the beads (Figure 5). At the highest concentration tested (5 μg/mL), the reactivities against IgG1, IgG3, and IgG4 were respectively: 0%, 45%, and 0% that of the reactivity against IgG2 (0.5μg per 1x106 beads of IgG subclass protein); 2%, 43%, and 3% (1μg per 1x106beads); and 2%, 61%, and 0% (2μg per 1x106 beads).