Patient characteristics after matching
A total of 114 uncomplicated IMHA patients who received the “wait-and-watch strategy” and had complete follow-up data in a single institution from January 2010 to December 2016 were included in this study (DM group [n=42], no DM group [n=67]). These two groups differed significantly in several covariables (including known risk factors for aortic diseases and known factors that could influence the progression and long-term outcomes of aortic diseases, Table 1 ) and became balanced after propensity score matching (Table 1and Supplement 1 ). Demographic characteristics after matching are shown in Table 2 . The median follow-up times for each group after matching were as follows: DM group (49.0 months, 95% confidence interval [CI], 45.5-52.5 months) and no-DM group (45.0 months, 95% CI, 42.2-47.8 months). The hyperglycemia was poorly controlled before hospitalization in DM group (Table 2 ). There were no statistically significant differences in the medical treatment strategy between the two groups (additional details in Table 2 ). In the DM group, the MMP-9 level was lower than no DM group (P< 0. 001, Figure 2 ) and reached the highest level (day 14) early than that in the no DM group (day 90).