Samples Patient 1 Patient 2 Patient 3 Patient 4 Patient 5
Maternal age (year) 42 40 31 44 37
Pregnancy history G1P0 G3P0 G1P0 G2P1 G2P1
Chorionicity DCDA DCDA DCDA DCDA DCDA
ART method IVF-ET IVF-ET IVF-ET IVF-ET IVF-ET
Number of embryo transfer 2 2 2 2 2
Gestational age for ultrasound (week) 13 14 12+5 12+6 12+5
Ultrasound examination
Fetus 1: NT 1.5mm; Fetus 2: NT 4.3mm, nasal bone loss, tricuspid regurgitation, single umbilical artery Fetus 1: NT 2.0mm; Fetus 2: NT 3.5mm, nasal bone loss, omphalocele Fetus 1: NT 1.8mm; Fetus 2: NT 2.0mm, nasal bone loss Fetus 1: NT 2.7mm, nasal bone loss, tricuspid regurgitation, single umbilical artery; Fetus 2: NT 2.5mm Fetus 1: NT 3.3mm; Fetus 2: NT 2.6mm, nasal bone loss, omphalocele
Prenatal diagnosis
Fetus 1: 46, XX; Fetus 2: 47, XX, +18 Fetus 1: 46, XY; Fetus 2: 47, XY, +18 Fetus 1: 46, XY; Fetus 2: 47, XX, +21 Fetus 1: 47, XX, +18; Fetus 2: 46, XY Fetus 1: 46, XX; Fetus 2: 47, XY, +18
Gestational age for reduction surgery (week) 14+3 14+0 17+4 15+5 14+5
Delivery One female with no apparent abnormalities One male with no apparent abnormalities One male with no apparent abnormalities One male with no apparent abnormalities One female with no apparent abnormalities
Gestational age of birth (weeks) 38+6 36+5 39+2 37+1 38+5