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Major thrombo-embolic complications in abdominal and lower limb arteries in COVID19 patients: a case series.
  • +2
  • giulia bonera,
  • giorgio nocivelli,
  • giorgio maria agazzi,
  • raffaele cuomo,
  • roberto maroldi
giulia bonera
Azienda Ospedaliera Spedali Civili di Brescia
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giorgio nocivelli
Azienda Ospedaliera Spedali Civili di Brescia
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giorgio maria agazzi
Azienda Ospedaliera Spedali Civili di Brescia
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raffaele cuomo
Azienda Ospedaliera Spedali Civili di Brescia
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roberto maroldi
Azienda Ospedaliera Spedali Civili di Brescia
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Peer review status:POSTED

24 Apr 2020Submitted to Journal of Evaluation in Clinical Practice
29 Apr 2020Assigned to Editor
29 Apr 2020Submission Checks Completed

Abstract

BACKGROUND: the outbreak of acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in more than 150000 infected individuals and more than 20000 deaths in Italy. Viral acute pneumonitis is the major cause of morbidity and mortality, but there is increasing evidence that COVID-19 patients show a variable degree of vascular complications, due to a possible hypercoagulability status. OBJECTIVE: to report thrombotic events in abdominal and lower-limb arteries of COVID-19 patients (abdominal aorta, superior mesenteric artery, femoral arteries, cardiac, spleen and kidney). METHODS: we retrospectively reviewed our clinical records of patients with confirmed SARS-CoV-2 infection, admitted from March 1st to April 6th, 2020, to a tertiary care center in Brescia, Italy. We selected five patients with major arterial thrombo-embolic manifestations. RESULTS AND CONCLUSION: In our opinion, arterial thrombotic events may be more common in COVID-19 patients than in general population, possibly resulting in rapid worsening of patient conditions.