10. References
Abaffy, T., Bain, J. R., Muehlbauer, M. J., Spasojevic, I., Lodha, S., Bruguera, E.,… & Matsunami, H. (2018). A testosterone metabolite 19-hydroxyandrostenedione induces neuroendocrine trans-differentiation of prostate cancer cells via an ectopic olfactory receptor. Frontiers in Oncology8 , 162.
Abaffy, T., Matsunami, H., & Luetje, C. W. (2006). Functional analysis of a mammalian odorant receptor subfamily. Journal of neurochemistry97 (5), 1506-1518.
Adipietro, K. A., Mainland, J. D., & Matsunami, H. (2012). Functional evolution of mammalian odorant receptors. PLoS genetics8 (7).
Aisenberg, W. H., Huang, J., Zhu, W., Rajkumar, P., Cruz, R., Santhanam, L., … & Yoon, A. R. (2016). Defining an olfactory receptor function in airway smooth muscle cells. Scientific reports6 , 38231.
Ali, B., Al-Wabel, N. A., Shams, S., Ahamad, A., Khan, S. A., & Anwar, F. (2015). Essential oils used in aromatherapy: A systemic review. Asian Pacific Journal of Tropical Biomedicine5 (8), 601-611.
Alok, K., Rakesh, T., & Sushil, K. (2000). Aromatherapy-an alternative health care through essential oils. Journal of Medicinal and Aromatic Plant Sciences22 (1B), 798-804.
Angelucci, F. L., Silva, V. V., Dal Pizzol, C., Spir, L. G., Praes, C. E. O., & Maibach, H. (2014). Physiological effect of olfactory stimuli inhalation in humans: An overview. International journal of cosmetic science36 (2), 117-123.
Ansoleaga, B., Garcia-Esparcia, P., Llorens, F., Moreno, J., Aso, E., & Ferrer, I. (2013). Dysregulation of brain olfactory and taste receptors in AD, PSP and CJD, and AD-related model. Neuroscience248 , 369-382.
Ansoleaga, B., Garcia-Esparcia, P., Pinacho, R., Haro, J. M., Ramos, B., & Ferrer, I. (2015). Decrease in olfactory and taste receptor expression in the dorsolateral prefrontal cortex in chronic schizophrenia. Journal of psychiatric research60 , 109-116.
Barros-Silva, J. D., Paulo, P., Bakken, A. C., Cerveira, N., Løvf, M., Henrique, R., … & Teixeira, M. R. (2013). Novel 5′ fusion partners of ETV1 and ETV4 in prostate cancer. Neoplasia (New York, NY)15 (7), 720.
Bezprozvanny, I., Scheller, R. H., & Tsien, R. W. (1995). Functional impact of syntaxin on gating of N-type and Q-type calcium channels. Nature378 (6557), 623-626.
Blowman, K., Magalhães, M., Lemos, M. F. L., Cabral, C., & Pires, I. M. (2018). Anticancer properties of essential oils and other natural products. Evidence-Based Complementary and Alternative Medicine2018 .
Braun, T., Voland, P., Kunz, L., Prinz, C., & Gratzl, M. (2007). Enterochromaffin cells of the human gut: sensors for spices and odorants. Gastroenterology132 (5), 1890-1901.
Breer, H. (2003). Olfactory receptors: molecular basis for recognition and discrimination of odors. Analytical and bioanalytical chemistry377 (3), 427-433.
Brenker, C., Goodwin, N., Weyand, I., Kashikar, N. D., Naruse, M., Krähling, M., … & Strünker, T. (2012). The CatSper channel: a polymodal chemosensor in human sperm. The EMBO journal31 (7), 1654-1665.
Brown, S. G., Publicover, S. J., Barratt, C. L., & Martins da Silva, S. J. (2019). Human sperm ion channel (dys) function: implications for fertilization. Human reproduction update25 (6), 758-776.
Buck, L. B. (2000). The molecular architecture of odor and pheromone sensing in mammals. Cell100 (6), 611-618.
Buck, L., & Axel, R. (1991). A novel multigene family may encode odorant receptors: a molecular basis for odor recognition. Cell65 (1), 175-187.
Busse, D., Kudella, P., Grüning, N. M., Gisselmann, G., Ständer, S., Luger, T., … & Böhm, M. (2014). A synthetic sandalwood odorant induces wound-healing processes in human keratinocytes via the olfactory receptor OR2AT4. Journal of investigative dermatology134 (11), 2823-2832.
Cao, W., Li, F., Yao, J., & Yu, J. (2015). Prostate specific G protein coupled receptor is associated with prostate cancer prognosis and affects cancer cell proliferation and invasion. BMC cancer15 (1), 915.
Chan, H. K., Hersperger, F., Marachlian, E., Smith, B. H., Locatelli, F., Szyszka, P., & Nowotny, T. (2018). Odorant mixtures elicit less variable and faster responses than pure odorants. PLoS computational biology14 (12), e1006536.
Chéret, J., Bertolini, M., Ponce, L., Lehmann, J., Tsai, T., Alam, M., … & Paus, R. (2018). Olfactory receptor OR2AT4 regulates human hair growth. Nature communications9 (1), 1-12.
Clark, A. A., Nurmukhambetova, S., Li, X., Munger, S. D., & Lees, J. R. (2016). Odorants specifically modulate chemotaxis and tissue retention of CD4+ T cells via cyclic adenosine monophosphate induction. Journal of leukocyte biology100 (4), 699-709.
Costa, C. G., Dorland, L., Holwerda, U., De Almeida, I. T., Jakobs, C., & Duran, M. (1998). Simultaneous analysis of plasma free fatty acids and their 3-hydroxy analogs in fatty acid β-oxidation disorders. Clinical chemistry44 (3), 463-471.
Cui, T., Tsolakis, A. V., Li, S. C., Cunningham, J. L., Lind, T., Öberg, K., & Giandomenico, V. (2013). Olfactory receptor 51E1 protein as a potential novel tissue biomarker for small intestine neuroendocrine carcinomas. European journal of endocrinology168 (2), 253-261.
Dalile, B., Van Oudenhove, L., Vervliet, B., & Verbeke, K. (2019). The role of short-chain fatty acids in microbiota–gut–brain communication. Nature Reviews Gastroenterology & Hepatology , 1.
Dalton, R. P., & Lomvardas, S. (2015). Chemosensory receptor specificity and regulation. Annual review of neuroscience38 , 331-349.
Denda, M., Tsuchiya, T., Shoji, K., & Tanida, M. (2000). Odorant inhalation affects skin barrier homeostasis in mice and humans. British Journal of Dermatology142 (5), 1007-1010.
Dhingra, D., Michael, M., Rajput, H., & Patil, R. T. (2012). Dietary fibre in foods: a review. Journal of food science and technology49 (3), 255-266.
Di Pizio, A., Behrens, M., & Krautwurst, D. (2019). Beyond the flavour: the potential druggability of chemosensory G Protein-Coupled receptors. International journal of molecular sciences20 (6), 1402.
Digby, G. J., Lober, R. M., Sethi, P. R., & Lambert, N. A. (2006). Some G protein heterotrimers physically dissociate in living cells. Proceedings of the National Academy of Sciences103 (47), 17789-17794.
Durzyński, Ł., Gaudin, J. C., Myga, M., Szydłowski, J., Goździcka-Józefiak, A., & Haertlé, T. (2005). Olfactory-like receptor cDNAs are present in human lingual cDNA libraries. Biochemical and biophysical research communications333 (1), 264-272.
Edwards, P. A., & Ericsson, J. (1999). Sterols and isoprenoids: signaling molecules derived from the cholesterol biosynthetic pathway. Annual review of biochemistry68 (1), 157-185.
Feldmesser, E., Olender, T., Khen, M., Yanai, I., Ophir, R., & Lancet, D. (2006). Widespread ectopic expression of olfactory receptor genes. BMC genomics7 (1), 121.
Ferrer, I., Garcia-Esparcia, P., Carmona, M., Carro, E., Aronica, E., Kovacs, G. G., … & Gustincich, S. (2016). Olfactory receptors in non-chemosensory organs: the nervous system in health and disease. Frontiers in aging neuroscience8 , 163.
Firestein, S. (2001). How the olfactory system makes sense of scents. Nature  413 (6852), 211-218.
Flegel, C., Manteniotis, S., Osthold, S., Hatt, H., & Gisselmann, G. (2013). Expression profile of ectopic olfactory receptors determined by deep sequencing. PloS one8 (2).
Flegel, C., Vogel, F., Hofreuter, A., Schreiner, B. S., Osthold, S., Veitinger, S., … & Altmüller, J. (2016). Characterization of the olfactory receptors expressed in human spermatozoa. Frontiers in molecular biosciences2 , 73.
Frank, M., Thümer, L., Lohse, M. J., & Bünemann, M. (2005). G protein activation without subunit dissociation depends on a Gαi-specific region. Journal of biological Chemistry280 (26), 24584-24590.
Fujita, Y., Takahashi, T., Suzuki, A., Kawashima, K., Nara, F., & Koishi, R. (2007). Deorphanization of Dresden G protein-coupled receptor for an odorant receptor. Journal of Receptors and Signal Transduction27 (4), 323-334.
Gainetdinov, R. R., Hoener, M. C., & Berry, M. D. (2018). Trace amines and their receptors. Pharmacological reviews70 (3), 549-620.
Garcia-Esparcia, P., Schlüter, A., Carmona, M., Moreno, J., Ansoleaga, B., Torrejón-Escribano, B., … & Ferrer, I. (2013). Functional genomics reveals dysregulation of cortical olfactory receptors in Parkinson disease: novel putative chemoreceptors in the human brain. Journal of Neuropathology & Experimental Neurology72 (6), 524-539.
Geithe, C., Andersen, G., Malki, A., & Krautwurst, D. (2015). A butter aroma recombinate activates human class-I odorant receptors. Journal of agricultural and food chemistry63 (43), 9410-9420.
Gelis, L., Jovancevic, N., Bechara, F. G., Neuhaus, E. M., & Hatt, H. (2017). Functional expression of olfactory receptors in human primary melanoma and melanoma metastasis. Experimental dermatology26 (7), 569-576.
Gelis, L., Jovancevic, N., Veitinger, S., Mandal, B., Arndt, H. D., Neuhaus, E. M., & Hatt, H. (2016). Functional characterization of the odorant receptor 51E2 in human melanocytes. Journal of Biological Chemistry291 (34), 17772-17786.
Giandomenico, V., Cui, T., Grimelius, L., Öberg, K., Pelosi, G., & Tsolakis, A. V. (2013). Olfactory Receptor 51E1 as a Novel Target for Diagnosis in Somatostatin Receptor Negative Lung Carcinoids. Journal of molecular endocrinology51 , 277-286.
Glusman, G., Bahar, A., Sharon, D., Pilpel, Y., White, J., & Lancet, D. (2000). The olfactory receptor gene superfamily: data mining, classification, and nomenclature. Mammalian genome11 (11), 1016-1023.
Glusman, G., Yanai, I., Rubin, I., & Lancet, D. (2001). The complete human olfactory subgenome. Genome research11 (5), 685-702.
Goldstein, J. L., & Brown, M. S. (1990). Regulation of the mevalonate pathway. Nature343 (6257), 425-430.
Griffin, C. A., Kafadar, K. A., & Pavlath, G. K. (2009). MOR23 promotes muscle regeneration and regulates cell adhesion and migration. Developmental cell17 (5), 649-661.
Grison, A., Zucchelli, S., Urzì, A., Zamparo, I., Lazarevic, D., Pascarella, G., … & Simone, R. (2014). Mesencephalic dopaminergic neurons express a repertoire of olfactory receptors and respond to odorant-like molecules. BMC genomics15 (1), 729.
Gu X. & Ben-Shahar Y. (2013) Olfactory Receptors in Human Airway Epithelia. In: Crasto C. (eds) Olfactory Receptors. Methods in Molecular Biology (Methods and Protocols), vol 1003. Humana Press, Totowa, NJ.
Gu, X., Karp, P. H., Brody, S. L., Pierce, R. A., Welsh, M. J., Holtzman, M. J., & Ben-Shahar, Y. (2014). Chemosensory functions for pulmonary neuroendocrine cells. American journal of respiratory cell and molecular biology50 (3), 637-646.
Guleria, S., Tiku, A. K., Koul, A., Gupta, S., Singh, G., & Razdan, V. K. (2013). Antioxidant and antimicrobial properties of the essential oil and extracts of Zanthoxylum alatum grown in North-Western Himalaya. The Scientific World Journal2013 .
Hartmann, C., Triller, A., Spehr, M., Dittrich, R., Hatt, H., & Buettner, A. (2013). Sperm‐Activating Odorous Substances in Human Follicular Fluid and Vaginal Secretion: Identification by Gas Chromatography–Olfactometry and Ca2+Imaging. ChemPlusChem78 (7), 695-702.
Hetherington-Rauth, M. C., & Ramírez, S. R. (2016). Evolution and diversity of floral scent chemistry in the euglossine bee-pollinated orchid genus Gongora. Annals of botany118 (1), 135-148.
Hutchings, C. J., Koglin, M., Olson, W. C., & Marshall, F. H. (2017). Opportunities for therapeutic antibodies directed at G-protein-coupled receptors. Nature reviews Drug discovery16 (11), 787.
Itakura, S., Ohno, K., Ueki, T., Sato, K., & Kanayama, N. (2006). Expression of Golf in the rat placenta: Possible implication in olfactory receptor transduction. Placenta27 (1), 103-108.
Jimbo, D., Kimura, Y., Taniguchi, M., Inoue, M., & Urakami, K. (2009). Effect of aromatherapy on patients with Alzheimer’s disease. Psychogeriatrics9 (4), 173-179.
Jones, D. T., & Reed, R. R. (1989). Golf: an olfactory neuron specific-G protein involved in odorant signal transduction. Science244 (4906), 790-795.
Jovancevic, N., Dendorfer, A., Matzkies, M., Kovarova, M., Heckmann, J. C., Osterloh, M., … & Hescheler, J. (2017a). Medium-chain fatty acids modulate myocardial function via a cardiac odorant receptor. Basic research in cardiology112 (2), 13.
Jovancevic, N., Wunderlich, K. A., Haering, C., Flegel, C., Maßberg, D., Weinrich, M., … & Wolfrum, U. (2017b). Deep sequencing of the human retinae reveals the expression of odorant receptors. Frontiers in cellular neuroscience11 , 3.
Kaji, I., Karaki, S. I., & Kuwahara, A. (2011). Effects of luminal thymol on epithelial transport in human and rat colon. American Journal of Physiology-Gastrointestinal and Liver Physiology300 (6), G1132-G1143.
Kako, H., Fukumoto, S., Kobayashi, Y., & Yokogoshi, H. (2008). Effects of direct exposure of green odour components on dopamine release from rat brain striatal slices and PC12 cells. Brain research bulletin75 (5), 706-712.
Kalbe, B., Knobloch, J., Schulz, V. M., Wecker, C., Schlimm, M., Scholz, P., … & Lübbert, H. (2016a). Olfactory receptors modulate physiological processes in human airway smooth muscle cells. Frontiers in physiology7 , 339.
Kalbe, B., Schlimm, M., Mohrhardt, J., Scholz, P., Jansen, F., Hatt, H., & Osterloh, S. (2016b). Helional induces Ca2+decrease and serotonin secretion of QGP-1 cells via a PKG-mediated pathway. J. Mol. Endocrinol57 , 201-210.
Kalbe, B., Schlimm, M., Wojcik, S., Philippou, S., Maßberg, D., Jansen, F., … & Hatt, H. (2016c). Olfactory signaling components and olfactory receptors are expressed in tubule cells of the human kidney. Archives of biochemistry and biophysics610 , 8-15.
Kalbe, B., Schulz, V. M., Schlimm, M., Philippou, S., Jovancevic, N., Jansen, F., … & Hecker, E. (2017). Helional-induced activation of human olfactory receptor 2J3 promotes apoptosis and inhibits proliferation in a non-small-cell lung cancer cell line. European journal of cell biology96 (1), 34-46.
Kaupp, U. B. (2010). Olfactory signalling in vertebrates and insects: differences and commonalities. Nature Reviews Neuroscience11 (3), 188-200.
Kaupp, U. B., Niidome, T., Tanabe, T., Terada, S., Bönigk, W., Stühmer, W., … & Miyata, T. (1989). Primary structure and functional expression from complementary DNA of the rod photoreceptor cyclic GMP-gated channel. Nature342 (6251), 762-766.
Kim, S. H., Yoon, Y. C., Lee, A. S., Kang, N., Koo, J., Rhyu, M. R., & Park, J. H. (2015). Expression of human olfactory receptor 10J5 in heart aorta, coronary artery, and endothelial cells and its functional role in angiogenesis. Biochemical and biophysical research communications460 (2), 404-408.
Koyano, S., Emi, M., Saito, T., Makino, N., Toriyama, S., Ishii, M., … & Kawata, S. (2008). Common null variant, Arg192Stop, in a G‐protein coupled receptor, olfactory receptor 1B1, associated with decreased serum cholinesterase activity. Hepatology Research38 (7), 696-703.
Lahlou, M. (2004). Essential oils and fragrance compounds: bioactivity and mechanisms of action. Flavour and Fragrance Journal19 (2), 159-165.
Lee, S. J., Depoortere, I., & Hatt, H. (2019). Therapeutic potential of ectopic olfactory and taste receptors. Nature Reviews Drug Discovery18 (2), 116-138.
Leja, J., Essaghir, A., Essand, M., Wester, K., Tötterman, T. H., Lloyd, R., … & Giandomenico, V. (2009). Novel markers for enterochromaffin cells and gastrointestinal neuroendocrine carcinomas. Modern pathology22 (2), 261-272.
Li, Y. R., & Matsunami, H. (2011). Activation state of the M3 muscarinic acetylcholine receptor modulates mammalian odorant receptor signaling. Science signaling4 (155), ra1-ra1.
Locatelli, F. F., Fernandez, P. C., & Smith, B. H. (2016). Learning about natural variation of odor mixtures enhances categorization in early olfactory processing. Journal of Experimental Biology219 (17), 2752-2762.
Luu, P., Acher, F., Bertrand, H. O., & Ngai, J. (2005). Odorant receptor specificities and receptor combinatorials: implications for olfactory coding. Chemical senses30 (suppl_1), i97-i98.
Ma, X., Guan, L., Wu, W., Zhang, Y., Zheng, W., Gao, Y. T., … & Xu, B. (2015). Whole-exome sequencing identifies OR2W3 mutation as a cause of autosomal dominant retinitis pigmentosa. Scientific reports5 (1), 1-6.
Macfarlane, S., & Macfarlane, G. T. (2003). Regulation of short-chain fatty acid production. Proceedings of the Nutrition Society62 (1), 67-72.
Mainland, J. D., Li, Y. R., Zhou, T., Liu, W. L. L., & Matsunami, H. (2015). Human olfactory receptor responses to odorants. Scientific data2 (1), 1-9.
Malik, B., Elkaddi, N., Turkistani, J., Spielman, A. I., & Ozdener, M. H. (2019). Mammalian Taste Cells Express Functional Olfactory Receptors. Chemical senses44 (5), 289-301.
Manteniotis, S., Wojcik, S., Brauhoff, P., Möllmann, M., Petersen, L., Göthert, J. R., … & Hatt, H. (2016a). Functional characterization of the ectopically expressed olfactory receptor 2AT4 in human myelogenous leukemia. Cell death discovery2 (1), 1-10.
Manteniotis, S., Wójcik, S., Göthert, J. R., Dürig, J., Dührsen, U., Gisselmann, G., & Hatt, H. (2016b). Deorphanization and characterization of the ectopically expressed olfactory receptor OR51B5 in myelogenous leukemia cells. Cell death discovery2 (1), 1-9.
Masjedi, S., Zwiebel, L. J., & Giorgio, T. D. (2019). Olfactory receptor gene abundance in invasive breast carcinoma. Scientific reports9 (1), 1-12.
Maßberg, D., & Hatt, H. (2018). Human olfactory receptors: novel cellular functions outside of the nose. Physiological reviews98 (3), 1739-1763.
Maßberg, D., Jovancevic, N., Offermann, A., Simon, A., Baniahmad, A., Perner, S., … & Heiland, M. (2016). The activation of OR51E1 causes growth suppression of human prostate cancer cells. Oncotarget7 (30), 48231.
Maßberg, D., Simon, A., Häussinger, D., Keitel, V., Gisselmann, G., Conrad, H., & Hatt, H. (2015). Monoterpene (−)-citronellal affects hepatocarcinoma cell signaling via an olfactory receptor. Archives of Biochemistry and Biophysics566 , 100-109.
Morita, R., Hirohashi, Y., Torigoe, T., Ito-Inoda, S., Takahashi, A., Mariya, T., … & Kubo, T. (2016). Olfactory Receptor Family 7 Subfamily C Member 1 Is a Novel Marker of Colon Cancer–Initiating Cells and Is a Potent Target of Immunotherapy. Clinical Cancer Research22 (13), 3298-3309.
Munakata, Y., Yamada, T., Imai, J., Takahashi, K., Tsukita, S., Shirai, Y., Kodama, S., Asai, Y., Sugisawa, T., Chiba, Y. and Kaneko, K. (2018). Olfactory receptors are expressed in pancreatic β-cells and promote glucose-stimulated insulin secretion. Scientific reports8 (1), pp.1-11.
Natarajan, N., & Pluznick, J. L. (2016). Olfaction in the kidney:‘smelling’gut microbial metabolites. Experimental physiology101 (4), 478-481.
Neuhaus, E. M., Mashukova, A., Barbour, J., Wolters, D., & Hatt, H. (2006). Novel function of β-arrestin2 in the nucleus of mature spermatozoa. Journal of cell science119 (15), 3047-3056.
Neuhaus, E. M., Zhang, W., Gelis, L., Deng, Y., Noldus, J., & Hatt, H. (2009). Activation of an olfactory receptor inhibits proliferation of prostate cancer cells. Journal of Biological Chemistry284 (24), 16218-16225.
Oh, S. J. (2018). System-wide expression and function of olfactory receptors in mammals. Genomics & informatics16 (1), 2.
Oldham, W. M., & Hamm, H. E. (2008). Heterotrimeric G protein activation by G-protein-coupled receptors. Nature reviews Molecular cell biology9 (1), 60-71.
Olender, T., Keydar, I., Pinto, J. M., Tatarskyy, P., Alkelai, A., Chien, M. S., … & Lancet, D. (2016). The human olfactory transcriptome. BMC genomics17 (1), 619.
Ottaviano, G., Zuccarello, D., Menegazzo, M., Perilli, L., Marioni, G., Frigo, A. C., … & Foresta, C. (2013). Human olfactory sensitivity for bourgeonal and male infertility: a preliminary investigation. European Archives of Oto-Rhino-Laryngology270 (12), 3079-3086.
Overington, J. P., Al-Lazikani, B., & Hopkins, A. L. (2006). How many drug targets are there?. Nature reviews Drug discovery5 (12), 993-996.
Parmentier, M., Libert, F., Schurmans, S., Schiffmann, S., Lefort, A., Eggerickx, D., … & Grootegoed, A. (1992). Expression of members of the putative olfactory receptor gene family in mammalian germ cells. Nature355 (6359), 453-455.
Perry, N., & Perry, E. (2006). Aromatherapy in the management of psychiatric disorders. CNS drugs20 (4), 257-280.
Peterlin, Z., Firestein, S., & Rogers, M. E. (2014). The state of the art of odorant receptor deorphanization: a report from the orphanage. Journal of General Physiology143 (5), 527-542.
Pichavant, C., Burkholder, T. J., & Pavlath, G. K. (2015). Decrease of myofiber branching via muscle-specific expression of the olfactory receptor mOR23 in dystrophic muscle leads to protection against mechanical stress. Skeletal muscle6 (1), 2.
Pichersky, E., Noel, J. P., & Dudareva, N. (2006). Biosynthesis of plant volatiles: nature’s diversity and ingenuity. Science311 (5762), 808-811.
Pick, H., Etter, S., Baud, O., Schmauder, R., Bordoli, L., Schwede, T., & Vogel, H. (2009). Dual activities of odorants on olfactory and nuclear hormone receptors. Journal of biological chemistry284 (44), 30547-30555.
Pluznick, J. L. (2013). Renal and cardiovascular sensory receptors and blood pressure regulation. American Journal of Physiology-Renal Physiology305 (4), F439-F444.
Pluznick, J. L. (2016). Gut microbiota in renal physiology: focus on short-chain fatty acids and their receptors. Kidney international90 (6), 1191-1198.
Ranzani, M., Iyer, V., Ibarra-Soria, X., Velasco-Herrera, M. D. C., Garnett, M., Logan, D., & Adams, D. J. (2017). Revisiting olfactory receptors as putative drivers of cancer. Wellcome open research2 .
Rigau, M., Morote, J., Mir, M. C., Ballesteros, C., Ortega, I., Sanchez, A., … & Planas, J. (2010). PSGR and PCA3 as biomarkers for the detection of prostate cancer in urine. The Prostate70 (16), 1760-1767.
Rodriguez, M., Luo, W., Weng, J., Zeng, L., Yi, Z., Siwko, S., & Liu, M. (2014). PSGR promotes prostatic intraepithelial neoplasia and prostate cancer xenograft growth through NF-κB. Oncogenesis3 (8), e114-e114.
Rooks, M. G., & Garrett, W. S. (2016). Gut microbiota, metabolites and host immunity. Nature Reviews Immunology16 (6), 341-352.
Rouquier, S., Taviaux, S., Trask, B. J., Brand-Arpon, V., van den Engh, G., Demaille, J., & Giorgi, D. (1998). Distribution of olfactory receptor genes in the human genome. Nature genetics18 (3), 243-250.
Saito, H., Chi, Q., Zhuang, H., Matsunami, H., & Mainland, J. D. (2009). Odor coding by a Mammalian receptor repertoire. Science signaling2 (60), ra9-ra9.
Santha, S., & Dwivedi, C. (2015). Anticancer effects of sandalwood (Santalum album). Anticancer research35 (6), 3137-3145.
Sanz, G., Leray, I., Dewaele, A., Sobilo, J., Lerondel, S., Bouet, S., … & Mir, L. M. (2014). Promotion of cancer cell invasiveness and metastasis emergence caused by olfactory receptor stimulation. PloS one9 (1).
Sanz, G., Schlegel, C., Pernollet, J. C., & Briand, L. (2005). Comparison of odorant specificity of two human olfactory receptors from different phylogenetic classes and evidence for antagonism. Chemical senses30 (1), 69-80.
Schiller, C., & Schiller, D. (1994). 500 formulas for aromatherapy: mixing essential oils for every use. Sterling Publishing Company, Inc, NY, USA.
Sharon, D., Kimchi, A., & Rivolta, C. (2016). OR2W3 sequence variants are unlikely to cause inherited retinal diseases. Ophthalmic genetics37 (4), 366-368.
Shepard, B. D., Cheval, L., Peterlin, Z., Firestein, S., Koepsell, H., Doucet, A., & Pluznick, J. L. (2016). A renal olfactory receptor aids in kidney glucose handling. Scientific reports6 , 35215.
Shiina, Y., Funabashi, N., Lee, K., Toyoda, T., Sekine, T., Honjo, S., … & Murakami, S. (2008). Relaxation effects of lavender aromatherapy improve coronary flow velocity reserve in healthy men evaluated by transthoracic Doppler echocardiography. International journal of cardiology129 (2), 193-197.
Sinding, C., Kemper, E., Spornraft-Ragaller, P., & Hummel, T. (2013). Decreased perception of bourgeonal may be linked to male idiopathic infertility. Chemical senses38 (5), 439-445.
Smith, C. A., Collins, C. T., Crowther, C. A., & Levett, K. M. (2011). Acupuncture or acupressure for pain management in labour. Cochrane Database of Systematic Reviews , (7).
Sondersorg, A. C., Busse, D., Kyereme, J., Rothermel, M., Neufang, G., Gisselmann, G., … & Conrad, H. (2014). Chemosensory information processing between keratinocytes and trigeminal neurons. Journal of Biological Chemistry289 (25), 17529-17540.
Spehr, J., Gelis, L., Osterloh, M., Oberland, S., Hatt, H., Spehr, M., & Neuhaus, E. M. (2011). G protein-coupled receptor signaling via Src kinase induces endogenous human transient receptor potential vanilloid type 6 (TRPV6) channel activation. Journal of Biological Chemistry286 (15), 13184-13192.
Spehr, M., Gisselmann, G., Poplawski, A., Riffell, J. A., Wetzel, C. H., Zimmer, R. K., & Hatt, H. (2003). Identification of a testicular odorant receptor mediating human sperm chemotaxis. Science299 (5615), 2054-2058.
Sprang, S. R. (2007). A receptor unlocked. Nature450 (7168), 355-356.
Strünker, T., Goodwin, N., Brenker, C., Kashikar, N. D., Weyand, I., Seifert, R., & Kaupp, U. B. (2011). The CatSper channel mediates progesterone-induced Ca 2+ influx in human sperm. Nature471 (7338), 382-386.
Tham, E. H., Dyjack, N., Kim, B. E., Rios, C., Seibold, M. A., Leung, D. Y., & Goleva, E. (2019). Expression and function of the ectopic olfactory receptor OR10G7 in patients with atopic dermatitis. Journal of Allergy and Clinical Immunology143 (5), 1838-1848.
Tong, T., Ryu, S. E., Min, Y., Claire, A., Bushdid, C., Golebiowski, J., … & Park, T. (2017). Olfactory receptor 10J5 responding to α-cedrene regulates hepatic steatosis via the cAMP–PKA pathway. Scientific reports7 (1), 1-13.
Tsai, T., Veitinger, S., Peek, I., Busse, D., Eckardt, J., Vladimirova, D., … & Ständer, S. (2017). Two olfactory receptors—OR 2A4/7 and OR 51B5—differentially affect epidermal proliferation and differentiation. Experimental dermatology26 (1), 58-65.
Veitinger, T., Riffell, J. R., Veitinger, S., Nascimento, J. M., Triller, A., Chandsawangbhuwana, C., … & Neuhaus, E. M. (2011). Chemosensory Ca2+ dynamics correlate with diverse behavioral phenotypes in human sperm. Journal of Biological Chemistry286 (19), 17311-17325.
Wang, J., Weng, J., Cai, Y., Penland, R., Liu, M., & Ittmann, M. (2006). The prostate‐specific G‐protein coupled receptors PSGR and PSGR2 are prostate cancer biomarkers that are complementary to α‐methylacyl‐CoA racemase. The Prostate66 (8), 847-857.
Weber, L., Al-Refae, K., Ebbert, J., Jägers, P., Altmüller, J., Becker, C., … & Hatt, H. (2017). Activation of odorant receptor in colorectal cancer cells leads to inhibition of cell proliferation and apoptosis. PLoS One12 (3).
Weber, L., Maßberg, D., Becker, C., Altmüller, J., Ubrig, B., Bonatz, G., … & Gisselmann, G. (2018a). Olfactory receptors as biomarkers in human breast carcinoma tissues. Frontiers in oncology8 , 33.
Weber, L., Schulz, W. A., Philippou, S., Eckardt, J., Ubrig, B., Hoffmann, M. J., … & Hatt, H. (2018b). Characterization of the olfactory receptor OR10H1 in human urinary bladder cancer. Frontiers in physiology9 , 456.
Weng, J., Ma, W., Mitchell, D., Zhang, J., & Liu, M. (2005). Regulation of human prostate‐specific G‐protein coupled receptor, PSGR, by two distinct promoters and growth factors. Journal of cellular biochemistry96 (5), 1034-1048.
Wennemuth, G., Carlson, A. E., Harper, A. J., & Babcock, D. F. (2003). Bicarbonate actions on flagellar and Ca2+-channel responses: initial events in sperm activation. Development130 (7), 1317-1326.
Wiese, H., Gelis, L., Wiese, S., Reichenbach, C., Jovancevic, N., Osterloh, M., … & Warscheid, B. (2015). Quantitative phosphoproteomics reveals the protein tyrosine kinase Pyk2 as a central effector of olfactory receptor signaling in prostate cancer cells. Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics1854 (6), 632-640.
Wildwood, C. (August 1, 1996). The encyclopedia of aromatherapy . Healing Arts Press, Rochester VT, USA.
Wojcik, S., Weidinger, D., Ständer, S., Luger, T., Hatt, H., & Jovancevic, N. (2018). Functional characterization of the extranasal OR 2A4/7 expressed in human melanocytes. Experimental dermatology27 (11), 1216-1223.
Woodward, M. R., Amrutkar, C. V., Shah, H. C., Benedict, R. H., Rajakrishnan, S., Doody, R. S., … & Szigeti, K. (2017). Validation of olfactory deficit as a biomarker of Alzheimer disease. Neurology: Clinical Practice7 (1), 5-14.
Wu, C., Hwang, S. H., Jia, Y., Choi, J., Kim, Y. J., Choi, D., … & Lee, S. J. (2017). Olfactory receptor 544 reduces adiposity by steering fuel preference toward fats. The Journal of clinical investigation127 (11), 4118-4123.
Wu, C., Jia, Y., Lee, J. H., Kim, Y., Sekharan, S., Batista, V. S., & Lee, S. J. (2015). Activation of OR1A1 suppresses PPAR-γ expression by inducing HES-1 in cultured hepatocytes. The international journal of biochemistry & cell biology64 , 75-80.
Xia, C., Ma, W., Wang, F., Hua, S. B., & Liu, M. (2001). Identification of a prostate-specific G-protein coupled receptor in prostate cancer. Oncogene20 (41), 5903-5907.
Xu, L. L., Stackhouse, B. G., Florence, K., Zhang, W., Shanmugam, N., Sesterhenn, I. A., … & Carter, K. (2000). PSGR, a novel prostate-specific gene with homology to a G protein-coupled receptor, is overexpressed in prostate cancer. Cancer research60 (23), 6568-6572.
Xu, L. L., Sun, C., Petrovics, G., Makarem, M., Furusato, B., Zhang, W., … & Srivastava, S. (2006). Quantitative expression profile of PSGR in prostate cancer. Prostate cancer and prostatic diseases9 (1), 56-61.
Xu, L., Tang, H., Chen, D. W., El‐Naggar, A. K., Wei, P., & Sturgis, E. M. (2015). Retracted: Genome‐wide association study identifies common genetic variants associated with salivary gland carcinoma and its subtypes. Cancer121 (14), 2367-2374.
Zhang, D., & Huang, X. (2015). Further consideration of the association between OR2W3 mutation and retinitis pigmentosa. Investigative ophthalmology & visual science56 (13), 8028-8028.
Zhao, W., Ho, L., Varghese, M., Yemul, S., Dams-O’Connor, K., Gordon, W., … & Pasinetti, G. M. (2013). Decreased level of olfactory receptors in blood cells following traumatic brain injury and potential association with tauopathy. Journal of Alzheimer’s Disease34(2), 417-429.