Prenatal / neonatal concordance
For the 75 cases, the final diagnosis based on post-natal CT-scan or post-operative conclusion was BC in 5 cases (7%), PCM in 5 cases (7%), hybrid malformations in 10 cases (13%), BPS in 25 cases (33%) and CLE in 30 cases (40%).
On postnatal evaluation, 35/75 (45%) patients had a systemic arterial supply, confirming a BPS or a hybrid malformation. Among them, 27 had a prenatal detection of a systemic arterial supply. In one case a systemic arterial supply was described in the prenatal ultrasound, but not confirmed after birth (one patient with CLE).
The prenatal detection of a systemic arterial supply had a sensitivity of 96%, a specificity of 83%, a positive predictive value of 77% and a negative predictive value of 98%.
On postnatal evaluation, 37/75 (49%) patients had a malformation with cystic component: BC, PCM or CLE associated to a bronchocele. Among them, 25 had a prenatal cystic component associated to the hyperechoic image. In 11 cases a cystic component was described in the prenatal ultrasound, but not confirmed after birth (CLE or BPS).
The prenatal detection of a cystic component had a sensitivity of 69%, a specificity of 69 %, a positive predictive value of 67% and a negative predictive value of 71%.