Parameter Basic model Basic model Final model Final model Bootstrap Bootstrap
Estimate
CV%
Estimate
CV%
Estimate
95%CI
CL (L/h) 1.07 13.0% 0.88 10.5% 0.90 0.74-1.11
V (L) 141.4 8.1% 148.8 7.5% 148.4 129.3-175.5
ka (h-1) 1.1(FIX) - 1.1(FIX) - 1.1(FIX) -
F (%) 86.4 7.5% 88.4 7.5% 89.4 78.1-106.4
PLT on CL - - 0.32 21.2% 0.32 0.08-0.52
TBIL on CL - - -0.57 -12.6% -0.57 -0.72- -0.44
WT on V - - 1.43 18.0% 1.42 0.86-1.96
ω2CL 68.3% 25.8% 18.0% 45.3% 18.0% 0.04-0.32
ω2V 15.3% 22.9% 12.0% 45.6% 12.0% 0.02-0.19
Proportional error 21.8% 10.3% 19.4% 10.0% 19.3% 0.15-0.2