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Chloroquine Phosphate is not proved to be an effective treatment for coronavirus
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  • Mohamed AllamOrcid
Mohamed Allam
Orcid
Ain Shams University Faculty of Medicine
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Peer review status:UNDER REVIEW

03 May 2020Submitted to International Journal of Clinical Practice
04 May 2020Assigned to Editor
04 May 2020Submission Checks Completed
05 May 2020Reviewer(s) Assigned

Abstract

The aim of this meta-analysis is to investigate the effectiveness of chloroquine in treating coronavirus, in general not only novel coronavirus (COVID¬-19), by pooling the results of randomized controlled clinical trials (RCTs). Only 28 publications were identified; none of which was a RCT. Identified studies were published between 1987 and March 15, 2020. Of these 28 publications, 7 were published in 2020 and discussed the effectiveness of chloroquine against COVID-19. In conclusion, this meta-analysis could not prove that chloroquine is an effective treatment against coronavirus in general or COVID-19 in particular. Expanded access trials should be encouraged especially that chloroquine is available, cheap and relatively safe drug.