Combination Therapy
Our presented technique is based on minimal surgery with ovary suppression with regard to endometriosis stage.
Combination therapy has been adopted as an approach for the management of endometriosis over the past 25 years(3). Given the lack of evidence on how estrogen levels affect endometriosis management, second and third look laparoscopy is suggested to follow the endometriosis lesion changes three and six months after GnRH agonist treatment, which is really helpful to decrease the endometriosis spots and lesions, deep penetration, and frozen pelvic (4).
GnRh-a pre-treatment leads to the resolution of lesions, decreases operation time and the occurrence of complications, which is useful to completely clear the tissue from serious infiltration or small retroperitoneal lesions through laparoscopic surgery.