2.2.1. Nigella sativa seed oil
N. sativa seed oil contain highly dose of thymoquinone, thymol, dithymoquinone, carvacrol, nigellimine-N-oxide, alpha-hederin and nigellicine [6]. It can be used to cure headache, nasal congestion, intermittent fever and dyspnea, and moreover, dried seeds can be used as inhalation to release cold. N. sativa components are used as immune-stimulatory and anti-inflammatory activity due tocytokines [7]. It is aninfluential, anti-inflammatory which inhibit the lipoxygenase and cyclooxygenase activities [8].