Conflict of interest
HHS has received honoraria for lectures and consulting from AbbVie, Amgen, AstraZeneca, Astropharma, Bano Healthcare, Chiesi, FOPI, Gebro, IIR, Janssen-Cilag, Lundbeck, MSD, Novartis, Pfizer, Roche, Sanofi-Aventis, Shire, Vertex (past 5 years). All other authors declare no conflicts of interest.