3.1.1. [3H]DA uptake inhibition in rat brain synaptosomes
Potencies of the tested compounds to inhibit DA uptake are depicted in Figure S1 and their respective IC50 values for [3H]DA uptake inhibition at DAT are compiled in Table 1. The rank order of potency inhibiting [3H]DA uptake was as follows: α-PVP>N-ethylpentedrone≈α-PpVP>pentedrone>>N,N-diethyl-pentedrone (F(4,14)=94.01).