3.1.1. [3H]DA uptake inhibition in rat brain
synaptosomes
Potencies of the tested compounds to inhibit DA uptake are depicted in
Figure S1 and their respective IC50 values for
[3H]DA uptake inhibition at DAT are compiled in
Table 1. The rank order of potency inhibiting
[3H]DA uptake was as follows:
α-PVP>N-ethylpentedrone≈α-PpVP>pentedrone>>N,N-diethyl-pentedrone
(F(4,14)=94.01).