Study design and population
We performed a cross-sectional study based on a systematic review of the most recent electronic prescriptions confirmed by interviewing all patients aged ≥65 years belonging to an HIV-infected cohort (Over50 cohort). The Over50 cohort is an ongoing prospective cohort of chronically HIV-infected people aged ≥50 years consecutively attended in our unit. All patients receive a comprehensive geriatric assessment covering medical, psychological, functional, and social aspects. Written informed consent was obtained from all participants before inclusion. The trial protocol was reviewed and approved by the clinical research ethics committee of the Germans Trias i Pujol Hospital (http://www.ceicgermanstrias.cat/) and met the criteria of the Declaration of Helsinki and the requirements of Good Clinical Practice (REF. CEI:  PI-16-068).