Supplementary File 2. Results of the single and combined
reaction perturbations (gene knock-out simulations) on SARS-CoV-2
production, as performed on all reactions identified as flux-carrying in
the flux variability analysis. Simulation results with the minimal media
with two different uptake flux limits are shown (flux limits set to -10
or -1000 mmol∙gDW-1∙h-1). Effects of
knock-outs are shown as percentage of optimal flux.