Table 3 Multivariate Logistic regression analysis of PD-L2 expression by clinicopathologic characteristics
3, MG and PD-L2 expression, clinicopathologic characteristics
Table 4 shows the compare of clinicopathologic characteristics between MG (+) group and MG (-) group. The patients with WHO histology of type B2 and B3 have a significantly higher incidence rate of MG (p=0.004). The patients with MG have smaller tumor size (p<0.001) and higher PD-L2 scores (p<0.001). No significantly difference were observed in age (p=0.052), gender (p=0.224), Masaoka-Koga stage (p=1) or ectopic thymus (p=0.357). Due to the positive association between MG and PD-L2 expression, we particularly analyzed the data of patients with MG to explore if the PD-L2 expression depended on the different features of MG (Table 5). 33 patients with MG were enrolled. There were no significantly difference of PD-L2 scores regarding gender, age, MGFA stage, WHO histology type, Masaoka-Koga stage, tumor size or ectopic thymus in patients with MG. We conducted a logistic regression model to predict PD-L2 expression in patients with MG. No feature listed above was associated with PD-L2 expression in patients with MG.