3.3 Risk factors of death in severe COVID-19 patients
127 severe patients (49 non-survivors and 78 survivors) were included in the univariate and multivariate logistic regression analysis. In the univariate analysis, odds of in-hospital death were higher in patients with chest tightness/dyspnea and smoking history (Table 4). Also, patients’ age, affected lobe number(s), leucocyte counts, levels of CRP, elevated NLR, PCT, BUN and serum creatinine were also associated with death (Table 4). The multivariate analysis revealed that age of patients (OR, 1.04; 95% CI, 1.00-1.08), the presence of smoking history (OR, 5.21; 95% CI, 1.39-19.52), chest tightness/dyspnea (OR, 3.03; 95% CI, 1.18-7.79), number of affected lobes on admission (OR, 1.71; 95% CI, 1.06-2.78) and level of CRP on admission (OR, 1.01; 95% CI, 1.00-1.02) were risk factors associated with death in cases with severe COVID-19 (Table 4, Fig. 1).