3.5.1 Vesivirus
Feline calicivirus, genus Vesivirus, familyCaliciviridae, is a highly contagious pathogen of domestic cats
and other Felidae (Gaskell et al., 2004). It typically causes
self-limiting upper respiratory tract disease (URTD) (Gaskell et al.,
2004). Recently enteric-adapted Feline calicivirus strains have
been isolated from cats with enteritis in single-agent infections or
together with other enteric viruses (Di Martino et al., 2020). Here,Feline calicivirus contigs were significantly more frequent in
FPV-cases (47.8%, 11/23) compared to healthy controls (13.9%, 5/36)
(p= 0.0067, Figure 2). With the exception of 2,889 and 6 reads from the
FPV-case and healthy control libraries, respectively, no Feline
calicivirus contigs were identified as Feline calicivirusvaccine strain F9. In contrast, 409,597 reads (320 RPM) mapped to theFeline calicivirus contigs identified in the FPV-case libraries
(Table 1). Feline calicivirus contigs identified in the other
nine FPV-case libraries ranged from 203 to 7864bp. In the control
libraries the longest Feline calicivirus contig was 815bp. The
phylogenetic analysis of the full genome and capsid protein shows the
enteric sequences in this study do not group with the other identified
enteric sequences in the phylogeny, instead forming a clade with other
sequences from Australia (Figure 5).