Conclusion:
HUS has many diverse presentations and etiologies, some of which are still poorly understood. Whereas HUS typically occurs in the pediatric population and is caused by EHEC, this case illustrates how HUS can also be found in adult patients and may be caused by other organisms such as EPEC. A thorough workup is required to identify HUS as the diagnosis and rule out other potential causes of MAHA and thrombocytopenia. Recognizing the different presentations and causes of HUS in adult patients is essential for conducting appropriate diagnostic studies and patient care.