Introduction
Cutaneous Leishmaniasis (CL) is a parasitic infectious disease which is
endemic in several countries around the world including Iran. This
infection is caused by a group of protozoan parasites of the genusLeishmania and is transmitted by the bite of infected female
phlebotomine sandflies. (1)
In Iran CL is mostly caused by Leishmania.major andLeishmania.tropica species. (2) The clinical features of CL
depend on various factors including Leishmania species,
environmental factors, genetic factors and immune response of the host.
(2) Innate and adaptive immune responses play an important part in
controlling leishmania infection and immunosuppression is a known risk
factor for unusual clinical variants of CL. (3, 4)
This case report highlights the unconventional clinical manifestation
and reactivation of CL in a patient undergoing systemic steroid therapy
and also demonstrates that the diagnosis could be challenging as it
mimics many other diseases.