Association between OD and aetiology with relevant
improvement in overall olfactory function
The next step included an analysis of associations between smell-loss
related factors: (i) age, (ii) gender, (iii) aetiology of smell loss
(infections, trauma, and idiopathic), (iv) duration of smell loss
(months), (v) duration of training (weeks), (vi) baseline olfactory
function, and (vii) presence of parosmia or phantosmia at initial visit
with clinically relevant recovery of overall olfactory function (defined
as TDI improvement greater or equal 5.5 points) at follow-up visit.
Therefore, a binary logistic regression model was computed.
Analysis revealed that relevant recovery of overall olfactory
performance was more likely in those that had lower baseline olfactory
function (adjusted odds ratio; aOR, 0.93; 95%CI, 0.88-0.97;Table 2 ), and postinfectious OD compared to posttraumatic (aOR,
0.28; 95%CI, 0.10-0.81) or idiopathic OD (aOR, 0.16; 95%CI,
0.06-0.41).