Development of Bing-Neel syndrome Despite Ibrutinib Therapy for
Waldenstrom Macroglobulinemia: Next Steps in Management and Review of
Bing-Neel syndrome (BNS) remains a rare complication of Waldenstrom
Macroglobulinemia. Given the paucity of this disease, treatment
guidelines are based on small clinical trials with limited participants.
Here we present a case of BNS that developed while on ibrutinib therapy,
followed by a review of the next steps in management.