Conclusion and Implications:
Our results clearly demonstrate that the barriers to developing a tetanus toxin therapeutic are not insurmountable and the technology presented here is the first major step towards realising the therapeutic potential of this powerful neurotoxin. Opening the therapeutic potential of tetanus toxin will have huge implication for the wide range of diseases caused by low-tone muscle.
Keywords: Tetanus toxin, muscle tone, sleep apnoea, protein therapeutic, immune evasion, immunological smokescreen, skeletal muscle