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Figure 1: Diagnostic algorithm for hypogammaglobulinemia (PID- Primary antibody deficiency, CVID- Common variable immunodeficiency, THI- Transient hypogammaglobulinemia of infancy, SPAD- Specific antibody deficiency, XL- X-linked, AD- Autosomal dominant, AR- Autosomal recessive, GOF- Gain-of-function)
Figure 2: Therapeutic algorithm for hypogammaglobulinemia (ATB- Antibiotics, IgRT- Immunoglobulin replacement therapy, AI- Aitoimmune, GLILD- Granulomatous-lymphocytic interstitial lung disease, IBD- Inflammatory bowel disease, LN- Lymph node)