Mitral bioprosthesis N= 174 Mitral mechanical prostheses N = 181
P value
Ventilation time (hours) 13.8 (9-18) 14.3 (8-20 ) 0.17
Intensive care unit stay (hours) 38.2 ± 15.7 46 ± 17 < 0.0001
Hospital stay (hours) 11.7 ± 2 15.5 ± 2.6 < 0.0001
New York Heart Association class 1.1 ± 0.4 1.2 ± 0.5 0.04
Wound infection (%) 2 (1.2%) 3 (1.7%) 0.82
Pericardial tamponade (%) 11 (6.5%) 17 (9.3% ) 0.33
Atrio-ventricular block grade III (%) 13 (7.3%) 16 (8.8%) 0.61
Atrial fibrillation (%) 37 (21%) 31 (17%) 0.34
Pneumonia (%) 17 (9.5%) 19 (10.5%) 0.82
Pneumothorax (%) 4 (2.4%) 9 (5%) 0.27
Pleural effusion (%) 6 (3.6%) 3 (1.7%) 0.19
Pacemaker implantation (%) 13 (7.3%) 14 (7.7%) 0.94
Acute renal failure (%) 16 (9%) 18 (10%) 0.75
Temporary dialysis (%) 3 (2%) 7 (3.7%) 0.27
Stroke (%) 6 (3.6%) 8 (4.4%) 0.66
Re-exploration for postoperative bleeding (%) 4 (2.4%) 18 (10%) < 0.0001
Immediate operative death 0 1 (0.6%)
30-day death (%) 1 (0.6%) 2 (1.2%) 0.29
30-day cardiac death (%)
0
0
30-day non-cardiac death (%)
1 (0.6%)
2 (1.2%)
0.29
10-year death (%) 6 (3.6%) 18 (10%) 0.01
10 year cardiac death
2 (1.2%)
12 (6.7%)
0.007
10-year non-cardiac death
4 (2.4%)
6 (3.3 % )
0.58
Mitral re-replacement 1 (0.6%) 7 (3.7%) 0.02
Abortion 5 (3%) 27 (15%) 0.0001
Abortion due to teratogenicity related to coumadin
-
18 (10%)
Abortion due to teratogenicity not related to coumadin
4 (2.4%)
5 (3%)
0.73
Abortion due to other causes (infection, physical problem, uterine anomalies)
1 (0.6%)
4 (2%)
0.25
Pregnancy free of anticoagulant complications 141 (81%) 101 (56%) < 0.0001
Echocardiographic data
Ejection fraction (%)
53 ± 11
52 ± 13
0.44
Left ventricular end diastolic diameter (cm)
5.1 ± 0.3
5 ± 0.6
0.05
Left ventricular end systolic diameter (cm)
3.7 ± 0.6
3.8 ± 0.5
0.08
Left atrium (cm)
4.3 ± 0.4
4.2 ± 0.6
0.07
Right atrium (cm)
4.7 (4.2-5.2)
4.8 (4.2-5.4)
0.09
Transprosthetic pressure gradient (mmHg)
7 ± 3
15 ± 4
< 0.0001
Pulmonary artery pressure (mmHg)
43 ± 5
42 ± 6
0.08
Width of the vena contracta (cm)
0.67 ± 0.08
0.64 ± 0.12
0.006