Conclusions:
Children aged less than five years with DKA have a higher risk of
developing CVC-associated VTE than similarly aged children with CVC
placement for any other reason. In our population, no demographic or
laboratory markers were found to effectively predict which children with
DKA would develop CVC-associated VTE. In accordance with published
guidelines, CVC use in the management of pediatric DKA should be avoided
if possible, but, if a CVC is placed, prophylaxis with standard or low
molecular weight heparin should be strongly considered for all patients
and the duration of CVC use should be limited by medical necessity.