Variables Methylation stage qRT-PCR stage
HCs 99 20
Sex ratio (M/F)
83/16
15/5
Age (years)
31.82 ± 8.71
31.85 ± 7.60
AS patients 99 20
Sex ratio (M/F)
77/22
14/6
Age (years)
31.14 ± 9.93
31.60 ± 7.86
Body mass index (Kg/m2)
22.58 ± 4.36
22.55 ± 3.03
Current smoker
37 (37.37)
8 (40.00)
Alcohol use
25 (25.25)
4 (20.00)
Propositus
63 (63.64)
15 (80.00)
Disease duration (years)
3.00 (1.00, 8.00)
2.00 (1.00, 8.50)
HLA-B27
91 (91.92)
18 (90.00)
ESR (mm/L)
15.50 (5.00, 32.50)
14.00 (7.75, 36.75)
CRP (m/L)
8.90 (2.22, 24.62)
6.65 (1.15, 31.14)
Ever treatment
72 (75.00)
14 (77.78)
SASP use
20 (20.83)
3 (20.00)
NSAIDs use
34 (35.42)
6 (40.00)
TNFi use
15 (15.63)
9 (60.00)
X-ray classification*
18
14
Level 1
2 (11.11)
4 (28.57)
Level 2
4 (22.22)
2 (14.29)
Level 3
9 (50.00)
7 (50.00)
Level 4
3 (16.67)
1 (7.14)
Global back pain (cm)
2.00 (1.00, 4.00)
0.00 (0.00, 3.00)
Finger-floor distance (cm)
6.00 (0.00, 19.00)
7.75 (0.00, 14.75)
Chest expansion (cm)
3.00 (2.00, 5.00)
3.50 (2.00, 5.50)
Schober test (cm)
6.00 (4.00, 10.00)
7.00 (5.00, 10.00)
Occipito wall gap (cm)
0.00 (0.00, 2.25)
0.00 (0.00, 1.50)
BASFI
0.90 (0.20, 2.20)
0.75 (0.03, 2.48)
BASDAI
2.10 (1.20, 3.50 )
2.35 (1.88, 3.35)
ASDAS
3.01 (2.10, 4.10)
2.74 (2.23, 4.12)