Results of meta-analysis
There were significant differences in serum resistin levels between CD patients and healthy controls, and CD patients had higher resistin concentrations (SMD = 1.76, 95% CI = 0.64 to 2.88, p = 0.002). Meanwhile, serum resistin levels in UC patients were also higher than that in healthy controls (SMD = 2.10, 95% CI = 1.03 to 3.17, p < 0.001 ) (Figure 2). In addition, subgroup analyses stratified by region showed that resistin levels of CD or UC patients had differences in Europe when compared with healthy controls, whereas no significant differences were found in non-Europe (Figure 3). Meta-regression analysis was applied for detecting additional sources of heterogeneity, indicated that publication year may be a source of heterogeneity across studies (Table 2).