Figure 1. Biological changes between GMPP and SMPP
(A) 2D scatter plot of the identified proteins which are detached in both GMPP and SMPP group. Proteins with log2FC more than 0.5 are thought as different expressed proteins and are colored with blue or red. Corresponding gene symbols of those proteins with log2FC more than 1.5 are labeled in the plot. (B, C) GO enrichment analysis results of the dysregulated genes which are enriched in SMPP group (B) and GMPP group (C). Top 15 with most significant enrichment results of each category (biological process, molecular function and cellular component) are showed. (D) KEGG enrichment analysis results of the dysregulated genes which are enriched in SMPP group (top) and GMPP group (bottom). All enrichment terms which reach enrichment significance are showed. (E) The overview of complement and coagulation cascades pathway. Genes in the box with color (green, grey and red) are the identified proteins in this pathway. The color intensity represents the corresponding log2FC level, increasing color intensity indicates that increasing enrichment level in SMPP group (red) and GMPP group (green).