2.8 Statistical analysis
All the statistical analyses were performed using R version 3.6.0 (https://www.r-project.org/). The T test was adopted to compare the significant difference level for continuous variables between GMPPs and SMPPs and Fisher’s exact test was implemented in categorical variables. Proteins with absolute value of Log2 fold change more than 0.5 between GMPP and SMPP were considered as differently expressed proteins. P-value or Benjamini-Hochberg adjusted P-value of less than 0.05 when executing multiple comparisons was considered as statistical significance.