Trial design
This was a prospective, single-center, RCT. A total of 955 patients with
KD at the Department of Cardiology of Guangzhou Women and Children’s
Medical Center fromJanuary 2018 toJune 2019 were selected and were
initially treated with IVIG. 80 patientswho were assessed as
IVIGresistant were randomly divided into two groupsusing a random number
table. TheResearch Ethics Committee of Guangzhou Women and Children’s
Medical Centerapprovedthis study (NO. GZR2015-099), and the children and
their families provided their written informed consent.The registration
number of this randomized controlled clinical trial is:
ChiCTR-EOC-17013266.